12 passenger airlines serve SNA with flights across the US, Canada, and Mexico.
| Airline | Terminal | Type |
|---|---|---|
| American Airlines | A | Major |
| Delta Air Lines | A | Major |
| Air Canada | A | International |
| Breeze Airways | A | Low-cost |
| WestJet | A | International |
| United Airlines | B | Major |
| Alaska Airlines | B | Major |
| Southwest Airlines | C | Major/Low-cost |
| Frontier Airlines | C | Ultra-low-cost |
| Allegiant Air | C | Ultra-low-cost |
| Spirit Airlines | C | Ultra-low-cost |
| JSX | ACI Jet FBO | Semi-private |